We are seeking highly-motivated Ph.D. students to join Dr. Yu Zhang’s lab at Michigan State University (Fall 2023, Spring 2024, Fall 2024. Multiple positions available).
The focus of the Zhang lab is to identify mechanisms that promote antibody diversification and suppress associated oncogenic lesions in lymphocytes. Antibody diversification generates the numerous antibodies in human body and plays a pivotal role in protecting us from infectious diseases and cancer. Abnormal antibody diversification underlies diseases ranging from immunodeficiency to autoimmunity and contributes to oncogenic translocations in various leukemias and lymphomas. The Zhang lab is particularly interested in how chromatin status and 3D genome architecture collaboratively contribute to the protective and pathogenic effect of antibody diversification. Projects will employ cell line and mouse models with a variety of state of art approaches, including CRIPSR/Cas9 mediated genome manipulation and various next generation sequencing techniques. The Zhang lab is well-funded by research grants from both NIH and NSF. The Ph.D. students can be fully supported by graduate assistantship and have the opportunity to closely collaborate with experts in immunology and bioinformatics.
Qualified applicants should:
1. Have B.S. or M.S. degree in Molecular Biology, Genetics, Genomics, Immunology or related biological science fields.
2. Be highly-motivated and passionate about scientific research.
3. Candidates with prior research experience in molecular biology are preferred.
If you are interested, please contact Dr. Zhang (yzhang22@msu.edu) with the following materials:
1. Curriculum vitae
2. Transcript
3. Contact information of three references.
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