[Neurobiology|Biochem] Postdoc position @ Shcheglovitov Lab, University of Utah

We are looking for a postdoc to study the properties of excitatory synapses in human stem cell-derived neurons and organoids. The main goal is to characterize SHANK3-binding partners in human synapses using biochemical and electrophysiological assays and to identify those that are lost or dysregulated by SHANK3 deficiency in association with autism and intellectual disability. We are particularly interested in receiving applications from creative and ambitious researchers with substantial experience in protein-protein interaction biochemistry or slice patch-clamp electrophysiology.

Check the following links and references to learn more about the Shcheglovitov lab in the Department of Neurobiology at the University of Utah, Salt Lake City, Utah.

Shcheglovitov lab: http://shcheglovitov-lab.utah.edu
Neurobiology Department: https://medicine.utah.edu/neurobiology-anatomy/
University of Utah: https://uofuhealth.utah.edu/why-utah.php
Salt Lake City: https://www.visitsaltlake.com
Utah: https://www.skiutah.com and https://utah.com/national-parks

Recent publications:
•  Wang et. al., 2021: “Modeling autism-associated SHANK3 deficiency using human cortico-striatal organoids generated from single neural rosettes”
BioRxiv doi: https://doi.org/10.1101/2021.01.25.428022
•  Chiola, Napan, Wang et al., 2021: “Defective AMPA-mediated synaptic transmission and morphology in human neurons with hemizygous SHANK3 deletion engrafted in mouse prefrontal cortex”
Molecular Psychiatry https://doi.org/10.1038/s41380-021-01023-2
•  Shcheglovitov A et al., 2013: “Shank3 and IGF1 Restore Synaptic Deficits in Neurons from 22q13 Deletion Syndrome Patients”,
Nature https://www.nature.com/articles/nature12618

If you are interested in this opportunity, please email your CV and a cover letter briefly describing your research interests and goals to Dr. Alex Shcheglovitov (alexsh@neuro.utah.edu).

PS: Salt Lake City是美国著名的滑雪胜地，邻近多个国家公园，喜欢户外运动的同学们不要错过！